CellSeal® AF-500™ Automated Fill and Seal System
Moving from concept to commercialization, the CealSeal AF-500 delivers the automation difference in a precision engineered, GMP compatible, fill-finish system. For cell and gene therapy developers and manufacturers, the AF-500 provides the path to scale up and standardization through increased accuracy, speed, and productivity. It’s versatile design for controlled environments include benchtops, biosafety cabinets, or an isolator.

Moving from concept to commercialization, the CellSeal AF-500 delivers the automation difference in a precision engineered, GMP compatible, fill-finish system.
- Automated filling and sealing of vials (ten 2 mL or 5 mL vials per set)
- Fills and seals 500 CellSeal vials in 90 minutes
- Transfers source material through needleless Luer fittings on the nozzle and the vials
- Customizable vial fill volume
- Filling accuracy is >99% for fill volumes from 0.8 mL to 5 mL
Data collection
- Multiple password controlled user levels
- Automatically generated batch records
- Up to 60 programmable parameters to optimize fill process
- Temperature of your source material may also be recorded
Fill System dimensions: 117.5 cm wide x 50.7 cm high x 50 cm deep
Electronic control cabinet dimensions: 60 cm wide x 45.1 cm high x 21 cm deep
Fill System weight: 95 kgs
Electrical cabinet weight: 30 kgs
Electricity: (108-125/220-245 VAC 50/60 Hz)
For use in biosafety cabinets or isolators
Compatible with vaporized hydrogen peroxide sterilization
Connection Kit
Description | Quantity Per Package | RPN |
Transfer kit | 1 per package | TK-500 |
CELLSEAL CRYOGENIC VIALS 10SET
Description | Quantity Per Box | RPN |
2 mL Needleless 10Set | 10 packs of 10 vials | CSV-047-10SET |
5 mL Needleless 10Set | 10 packs of 10 vials | CSV-049-10SET |
DISCLAIMER: Unless otherwise noted, CellSeal products are intended for laboratory research, bioprocessing, or manufacturing use only. Any use for diagnostic purposes, direct transfusion, or in the production of therapeutic product(s) or vaccine(s) may require advance regulatory review or approval. Determining the need for and seeking regulatory approval is the sole responsibility of the CellSeal product user. Cook Regentec will provide support in the form of testing data or Master File cross reference authorization as available and upon request. If you have any questions, please contact us